This article provides an overview of the latest research on the pathogenesis, diagnosis, and treatment strategies for retinitis pigmentosa (RP). Please note that the authors of this paper chose to review only non-syndromic RP. The authors explain the molecular biology behind various methods by which the cells in the retina atrophy (die). They emphasize the promise of technologies such as delivery vectors, CRISPR/cas9 for genetic modification and the use of induced pluripotent stem cells (iPSCs) for cell transplant which are contributing to the overall advancement of personalized treatment for RP.
What this means for Usher syndrome: All research on retinitis pigmentosa, even if it doesn’t include the exact genes that are known to cause Usher syndrome (USH), improves knowledge which gives USH researchers a path to pave the way for improved diagnostic methods and treatment approaches.
